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The SEXSI trial is a pragmatic, assessor and participant blinded, randomized, controlled, superiority trial, with a two-group parallel design.

Patients with subacromial impingement syndrome will be randomized to either usual care or a home-based intervention consisting of progressive high volume resistance training in addition to usual care using a 1:1 allocation.

The outcome at 16 weeks will be included as dependent variable, treatment group (IG or CG) as main effect and both baseline score and any additional follow up measurements as repeated measurements.

The covariance structures will be selected based on the MAICE procedure.

Instructions provided 0, 2, 5, and 10 weeks after baseline.

Usual care includes all treatment received by a patient during the time between baseline and follow-up, except that included in "Strengthen your Shoulder".

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Listing a study does not mean it has been evaluated by the U. Half of the participants receive instructions in simple home-based elastic band strengthening exercises in addition to usual care, while the other half receive usual care.Usual care, consisting of a referral to general rehabilitation in the municipal under the Danish Health Act § 140, most often with the alternative option to choose a private physiotherapeutic clinic, partly at their own expense.Also includes any additional treatment the patient receives between baseline and follow-up, except that included in "Strengthen your Shoulder".The primary end-point will be change in the Shoulder Pain and Disability Index (SPADI) 16 weeks after baseline.The overall frame for the trial is a main clinical effectiveness-part and an embedded mechanistic part.

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